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Image Search Results
Journal: bioRxiv
Article Title: Chronic intestinal immune activation reveals separable impacts of inflammation and barrier loss on hallmarks of ageing
doi: 10.1101/2025.08.11.669650
Figure Lengend Snippet: (A & B) Normalised mRNA level for Snakeskin (A, Ssk) and Mesh (B) in dissected whole gut samples from TiGS>UAS-PGRP-Lc non-Smurf and Smurf females fed RU486 and controls. n = 6 samples, 5 guts/sample. (C & D) Gut diameter at days 3 and 7 (C) and pH3+ cell counts at day 7 (D) post RU486 feeding from TiGS>UAS-PGRP-Lc non-Smurf females. (E) pH3+ cell counts at 25 days of age (15 days post RU486 feeding) from TiGS>UAS-PGRP-Lc non-Smurf and Smurf females fed RU486 and controls. N = (F & G) pH3+ cell counts in non-Smurf TiGS>UAS-PGRP-Lc female midguts at day 7 post RU486 and Gemcitabine feeding (F) and Smurf proportions at 15 days post RU486 and Gemcitabine feeding (23 days old) (G).Bar graphs show mean ± SEM. Boxplots display the 25-75 th percentiles, with the horizontal bar at the median, and whiskers extending from the minimum to maximum points. Two-way Anova with Tukey’s multiple comparisons (A, B & E). Mann Whitney U (C & D) Kruskal-Wallis with Dunn’s post hoc test (F) Binomial test (G) *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
Article Snippet: Samples were immunostained with primary antibody (
Techniques: MANN-WHITNEY